Section · Administrative Rules of South Dakota · View on sdlegislature.gov ↗
A prescription may not be refilled except as designated on the original prescription or as subsequently authorized by the prescriber. Each refill must be entered on the back of the original prescription or captured electronically and must include the quantity dispensed, the date refilled, and the initials or name of the dispensing pharmacist. Any prescription renewed by the prescriber constitutes a new and separate prescription, must be assigned a new serial number, and is subject to the restrictions in this section. A noncontrolled legend drug may only be refilled for the total quantity on the prescription and not filled or refilled after twelve months from the original date of the prescription's issuance. If the prescriber is unable to be contacted to authorize a refill, the pharmacist may refill up to a thirty-day supply of the noncontrolled legend drug, if, in the professional judgement of the pharmacist, the drug is necessary to maintain the patient's health. A Schedule III or IV controlled drug may only be refilled as authorized on the prescription and up to five times within six months after the date of the prescription's issuance. The partial dispensing of refills may not exceed the total quantity authorized on the prescription. A Schedule II controlled drug may not be refilled. A pharmacist may partially fill a prescription for a Schedule II controlled drug according to the procedures set forth in §§ 44:58:08:18 and 44:58:08:18.01, and 21 C.F.R. §§ 1306.12 and 1306.13 (April 2, 2026). A prescription for a Schedule II controlled drug may not be filled later than six months after the date of issuance.
Source: 53 SDR 13, effective August 16, 2026.